Paul L. Modrich: search on Z-Library

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1

Engineering Life: Building a FAB for Biology

Baker, David, Church, George, Collins, Jim, Endy, Drew, Jacobson, Joseph, Keasling, Jay, Modrich, Paul, Smolke, Christina, Weiss, Ron

Journal:

Scientific American

Year:

2006

Language:

english

File:

PDF, 832 KB

english, 2006

2

DNA Mismatch Repair: Functions and Mechanisms

Iyer, Ravi R., Pluciennik, Anna, Burdett, Vickers, Modrich, Paul L.

Journal:

Chemical Reviews

Year:

2006

Language:

english

File:

PDF, 647 KB

english, 2006

3

Mismatch Repair in Replication Fidelity, Genetic Recombination, and Cancer Biology

Modrich, Paul, Lahue, Robert

Journal:

Annual Review of Biochemistry

Year:

1996

Language:

english

File:

PDF, 2.08 MB

english, 1996

4

Structure of the Human MutSα DNA Lesion Recognition Complex

Joshua J. Warren, Timothy J. Pohlhaus, Anita Changela, Ravi R. Iyer, Paul L. Modrich, Lorena S. Beese

Journal:

Year:

2007

Language:

english

File:

PDF, 3.02 MB

english, 2007

5

Christian Raetz: Scientist and Friend Extraordinaire

Dowhan, William, Nikaido, Hiroshi, Stubbe, JoAnne, Kozarich, John W., Wickner, William T., Russell, David W., Garrett, Teresa A., Brozek, Kathryn, Modrich, Paul

Journal:

Annual Review of Biochemistry

Year:

2013

Language:

english

File:

PDF, 1.85 MB

english, 2013

6

Therapeutic efficacy of vinorelbine against pediatric and adult central nervous system tumors

Matthew L. Hanley, Gertrude B. Elion, O. Michael Colvin, Paul L. Modrich, Stephen Keir, David J. Adams, Darell D. Bigner, Henry S. Friedman

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1998

Language:

english

File:

PDF, 131 KB

english, 1998

7

Modulation of MutS ATP Hydrolysis by DNA Cofactors †

Bjornson, Keith P., Allen, Dwayne J., Modrich, Paul

Journal:

Year:

2000

Language:

english

File:

PDF, 98 KB

english, 2000

8

Substrate dependence of the mechanism of EcoRI endonuclease

Rubin, Robert A., Modrich, Paul

Journal:

Nucleic Acids Research

Year:

1978

Language:

english

File:

PDF, 341 KB

english, 1978

9

A Structural Basis for a Phosphoramide Mustard-Induced DNA Interstrand Cross-Link at 5'-d(GAC)

Qing Dong, Daniel Barsky, Michael E. Colvin, Carl F. Melius, Susan M. Ludeman, Jonathan F. Moravek, O. Michael Colvin, Darell D. Bigner, Paul Modrich and Henry S. Friedman

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.24 MB

english, 1995

10

CAF-I-dependent control of degradation of the discontinuous strands during mismatch repair

Lyudmila Y. Kadyrova, Elena Rodriges Blanko, Farid A. Kadyrov and Paul Modrich

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.47 MB

english, 2011

11

Mechanism of 5′-Directed Excision in Human Mismatch Repair

Jochen Genschel, Paul Modrich

Journal:

Year:

2003

Language:

english

File:

PDF, 373 KB

english, 2003

12

Mechanisms in Eukaryotic Mismatch Repair

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 711 KB

english, 2006

13

Restoration of Mismatch Repair to Nuclear Extracts of H6 Colorectal Tumor cells by a Heterodimer of Human MutL Homologs

Guo-Min Li and Paul Modrich

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 898 KB

english, 1995

14

Structures and mechanisms of DNA restriction and modification enzymes

Journal:

Quarterly Reviews of Biophysics

Year:

1979

Language:

english

File:

PDF, 2.74 MB

english, 1979

15

Crystal Structures of Human Exonuclease I with DNA Provides Insight into Substrate Selectivity and Mechanism

Orans, Jillian, McSweeney, Elizabeth, Modrich, Paul, Beese, Lorena S.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 41 KB

english, 2011

16

DHFR/MSH3 Amplification in Methotrexate-Resistant Cells Alters the hMutsα /hMutSβ Ratio and Reduces the Efficiency of Base-Base Mismatch Repair

James T. Drummond, Jochen Genschel, Elisabeth Wolf and Paul Modrich

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.59 MB

english, 1997

17

HIF-1α Induces Genetic Instability by Transcriptionally Downregulating MutSα Expression

Minori Koshiji, Kenneth K.-W. To, Stefanie Hammer, Kensuke Kumamoto, Adrian L. Harris, Paul Modrich, L. Eric Huang

Journal:

Year:

2005

Language:

english

File:

PDF, 652 KB

english, 2005

18

Obituary

Orans, Jillian, McSweeney, Elizabeth, Modrich, Paul, Beese, Lorena S.

Journal:

Year:

1986

Language:

english

File:

PDF, 198 KB

english, 1986

19

Removal of Polymerase-Produced Mutant Sequences from PCR Products

Jane Smith and Paul Modrich

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 674 KB

english, 1997

20

DNA Repair and Recombination || Mismatch Repair, Genetic Stability and Tumour Avoidance

Journal:

Philosophical Transactions Biological Sciences

Year:

1995

Language:

english

File:

PDF, 1022 KB

english, 1995

21

Methyl-directed DNA mismatch repair in Escherichia coli

Robert S. Lahue, Paul Modrich

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1988

Language:

english

File:

PDF, 590 KB

english, 1988

22

Studies on Sequence Recognition By Type II Restriction and Modification Enzyme

Journal:

Critical Reviews in Biochemistry and Molecular Biology

Year:

1982

Language:

english

File:

PDF, 2.83 MB

english, 1982

23

Nucleotide sequence of a cDNA for a member of the human 90-kDa heat-shock protein family

Rebbe, Neil F., Ware, Jerry, Bertina, Rogier M., Modrich, Paul, Stafford, Darrel W.

Journal:

Year:

1987

Language:

english

File:

PDF, 1.60 MB

english, 1987

24

‘Interactive’ recognition in Eco Rl restriction enzyme-DNA complex

Kim, Rosalind, Modrich, Paul, Kim, Sung-Hou

Journal:

Nucleic Acids Research

Year:

1984

Language:

english

File:

PDF, 1.93 MB

english, 1984

25

An Alkylation-Tolerant, Mutator Human Cell Line is Deficient in Strand-Specific Mismatch Repair

Alexandra Kat, William G. Thilly, Woei-Horng Fang, Matthew J. Longley, Guo-Min Li and Paul Modrich

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1017 KB

english, 1993

26

Interaction of proliferating cell nuclear antigen with PMS2 is required for MutLα activation and function in mismatch repair

Genschel, Jochen, Kadyrova, Lyudmila Y., Iyer, Ravi R., Dahal, Basanta K., Kadyrov, Farid A., Modrich, Paul

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 943 KB

english, 2017

27

hMutSα - and hMutLα -Dependent Phosphorylation of p53 in Response to DNA Methylator Damage

Derek R. Duckett, S. Maynard Bronstein, Yoichi Taya and Paul Modrich

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.10 MB

english, 1999

28

Mapping Individual Cosmid DNAs by Direct AFM Imaging

David P. Allison, Peggy S. Kerper, Mitchel J. Doktycz, Thomas Thundat, Paul Modrich, Frank W. Larimer, Dabney K. Johnson, Peter R. Hoyt, Michael L. Mucenski, Robert J. Warmack

Journal:

Year:

1997

Language:

english

File:

PDF, 587 KB

english, 1997

29

PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair

Anna Pluciennik, Leonid Dzantiev, Ravi R. Iyer, Nicoleta Constantin, Farid A. Kadyrov and Paul Modrich

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.25 MB

english, 2010

30

Direct Visualization of Asymmetric Adenine Nucleotide-Induced Conformational Changes in MutLα

Elizabeth J. Sacho, Farid A. Kadyrov, Paul Modrich, Thomas A. Kunkel, Dorothy A. Erie

Journal:

Year:

2008

Language:

english

File:

PDF, 1004 KB

english, 2008

31

Mechanismen der Fehlpaarungsreparatur in E. coli und im Menschen (Nobel-Aufsatz)

Journal:

Angewandte Chemie

Year:

2016

Language:

german

File:

PDF, 3.88 MB

german, 2016

32

Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture)

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 3.96 MB

english, 2016

33

A phase II window trial of procarbazine and topotecan in children with high-grade glioma: a report from the children’s oncology group

Murali M. Chintagumpala, Henry S. Friedman, Clinton F. Stewart, James Kepner, Roger E. McLendon, Paul L. Modrich, Charles McCluggage, Peter Burger, Emi Holmes, Stephen Thompson, James Rutka, Jeff Mich

Journal:

Journal of Neuro-Oncology

Year:

2006

Language:

english

File:

PDF, 197 KB

english, 2006

34

Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family

Jillian Orans, Elizabeth A. McSweeney, Ravi R. Iyer, Michael A. Hast, Homme W. Hellinga, Paul Modrich, Lorena S. Beese

Journal:

Year:

2011

Language:

english

File:

PDF, 2.04 MB

english, 2011

35

Genetic and enzymatic characterization of a conditional lethal mutant of Escherichia coli K12 with a temperature-sensitive DNA ligase

E.Bruce Konrad, Paul Modrich, I.R. Lehman

Journal:

Journal of Molecular Biology

Year:

1973

Language:

english

File:

PDF, 681 KB

english, 1973

36

Somatic mutation of hPMS2 as a possible cause of sporadic human colon cancer with microsatellite instability

Ma, Ai-Hong, Xia, Liang, Littman, Susan J, Swinler, Sandra, Lader, Gabriel, Polinkovsky, Alexander, Olechnowicz, Joseph, Kasturi, Lakshmi, Lutterbaugh, James, Modrich, Paul

Journal:

Year:

2000

Language:

english

File:

PDF, 195 KB

english, 2000

37

Escherichia coli mutY Gene Product is Required for Specific A-G→ C· G Mismatch Correction

K. G. Au, M. Cabrera, J. H. Miller and Paul Modrich

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 760 KB

english, 1988

38

Enzymatic Characterization of a Mutant of Escherichia coli with an Altered DNA Ligase

Paul Modrich and I. R. Lehman

Journal:

Proceedings of the National Academy of Sciences

Year:

1971

Language:

english

File:

PDF, 699 KB

english, 1971

39

Biallelic Inactivation of hMLH1 by Epigenetic Gene Silencing, a Novel Mechanism Causing Human MSI Cancers

Martina L. Veigl, Lakshmi Kasturi, Joseph Olechnowicz, AiHong Ma, James D. Lutterbaugh, Sumudra Periyasamy, Guo-Min Li, James Drummond, Paul L. Modrich, W. David Sedwick and Sanford D. Markowitz

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.42 MB

english, 1998

40

MSH6, a Saccharomyces cerevisiae protein that binds to mismatches as a heterodimer with MSH2

Ingram Iaccarino, Fabio Palombo, James Drummond, Nicholas F. Totty, J.Justin Hsuan, Paul Modrich, Josef Jiricny

Journal:

Current Biology

Year:

1996

Language:

english

File:

PDF, 280 KB

english, 1996

41

[Part 1: Biological Sciences] || Methyl-Directed Repair of DNA Base-Pair Mismatches in vitro

A.-Lien Lu, Susanna Clark and Paul Modrich

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 1.29 MB

english, 1983

42

Mutation Detection with MutH, MutL, and MutS Mismatch Repair Proteins

Jane Smith and Paul Modrich

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1018 KB

english, 1996

43

A Defined Human System That Supports Bidirectional Mismatch-Provoked Excision

Leonid Dzantiev, Nicoleta Constantin, Jochen Genschel, Ravi R. Iyer, Peter M. Burgers, Paul Modrich

Journal:

Year:

2004

Language:

english

File:

PDF, 388 KB

english, 2004

44

Early thinking on the nature of mismatch repair

Journal:

Year:

2005

Language:

english

File:

PDF, 2.78 MB

english, 2005

45

Structure of the Endonuclease Domain of MutL: Unlicensed to Cut

Monica C. Pillon, Jessica J. Lorenowicz, Michael Uckelmann, Andrew D. Klocko, Ryan R. Mitchell, Yu Seon Chung, Paul Modrich, Graham C. Walker, Lyle A. Simmons, Peter Friedhoff, Alba Guarné

Journal:

Year:

2010

Language:

english

File:

PDF, 910 KB

english, 2010

46

Preliminary X-ray diffraction studies of EcoRI restriction endonuclease-DNA complex

Ti-Sheng Young, Sung-Hou Kim, Paul Modrich, Akum Beth, Ernest Jay

Journal:

Journal of Molecular Biology

Year:

1981

Language:

english

File:

PDF, 4.66 MB

english, 1981

47

Hypermutability and mismatch repair deficiency in RER+ tumor cells

Ramon Parsons, Guo-Min Li, Matthew J. Longley, Woei-horng Fang, Nickolas Papadopoulos, Jin Jen, Albert de la Chapelle, Kenneth W. Kinzler, Bert Vogelstein, Paul Modrich

Journal:

Year:

1993

Language:

english

File:

PDF, 1.51 MB

english, 1993

48

Escherichia coli mutS-Encoded Protein Binds to Mismatched DNA Base Pairs

Shin-San Su and Paul Modrich

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 1.08 MB

english, 1986

49

Human MutSα Recognizes Damaged DNA Base Pairs Containing O6-Methylguanine, O4-Methylthymine, or the Cisplatin-d(GpG) Adduct

Derek R. Duckett, James T. Drummond, Alastair I. H. Murchie, Joyce T. Reardon, Aziz Sancar, David M. J. Lilley and Paul Modrich

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 965 KB

english, 1996

50

Human Exonuclease I Is Required for 5′ and 3′ Mismatch Repair

Genschel, Jochen, Bazemore, Laura R., Modrich, Paul

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 844 KB

english, 2002

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